Corrupted Brain Stem:

The wielder of the Corrupted Brain Stem increases their Cunning by 4, and their Cunning cap by 2. All rolls that use Cunning also add a d4. However, they also increase their chance to die per session by 5% per point of Cunning they possess. Their chance of death cannot be reduced below this number. If this artifact is ever unequipped, the wielder immediately dies.